Topics for Chapter 5: Protein functions

Myoglobin and Hemoglobin

Heme chemistry

Hyperbolic and sigmoidal kinetics

T and R state description

Mechanism of hemoglobin cooperativity

Details of heme interaction

Details of structural rearrangements

Mutant hemoglobins

globin evolution

 

Immunoglobins

IgG structure

Antibody function

Motor proteins

Structure and function of actin and myosin